Parkinson’s disease may have an infectious origin

A team from the Consortium of Ivestigaci’n Neurogenética of the united States has discovered new evidence that Parkinson’s disease may have an infectious origin or autoimmune, as are variations in genes of the region’re HLA, which contains a large n&number;number of genes related to the function’n system immune’logical in human beings. S&number;n have been explained to the authors, this region’n it is essential for the recognition of foreign invaders in the tissues of the body. In the same way, the moléflecks HLA recognize the body’s own tissue as itself and así to prevent immune reactions against them.

however, the system does not always work perfectly, there are actually HLA genes that varían from one person to another, which may be associated with an increased risk or protection’n against infectious disease while other variants can induce autoimmune diseases in which the immune system attacks the own tissues of the body. For example, the sclerosis m&number;multiple, disease neurol’gica caused by autoimmunity, but alsoén is associated with HLA-DR, a variant geneética the researchers have now been associated with Parkinson’s disease. The team has studied in más 2,000 Parkinson’s disease patients and 2,000 healthy volunteers from hospitals in Oregon, Washington, New York and Georgia, the evaluation’n of the factors clínicos, genéticos, and environmental that may contribute to the development and progression you’re the Parkinson’s disease and its complications. Some of the subjects in the study were followed for almost two dérock. "for a&bath;os is is giving a suspicion that the function’re immune, couldíto be linked to Parkinson’s disease", has indicated one of the directors of the study, dr. Cyrus Zabetian, associate professor of neurología in the University of Washington. IBUPROFEN CAN REDUCE the RISK OF THE DEVELOPMENT OF THE DISEASE The doctor has explained that people who take nonsteroidal anti-inflammatory drugs (NSAIDS, such as ibuprofen) have a reduced risk of developing Parkinson’s disease, which alsoén supports an immune mechanism-related. Although it has been&bath;winged that the protective effect of NSAIDS is not the same for all, probably due to the differences of geneéticas, and además has remembered that NSAIDS can have side effects. Now that you know the link’n between Parkinson’s disease and chronic inflammation’n, especially in the context of the composition’n genética variable, it is possible to drive drugs más targeted for the treatment of Parkinson’s disease. Zabetian has been claimed that these results alsoén have been referred to by other genes that can’w performance&bath;ar a role in the development of this disease, but these findings need yet’to be confirmed, así continueán working on this línea.